β cell antigen recognition by CD4 T cells T cell promiscuity in autoimmune diabetes

نویسندگان

  • Li Li
  • Bo Wang
  • Jeffrey A. Frelinger
  • Roland Tisch
  • Mary Ellen Jones
چکیده

Abbreviations: CAT, chloroform acetyltransferase; CDR, complementary determining region; EAE, experimental autoimmune encephalomyelitis; GAD65, glutamic acid decarboxylase 65; HEL, hen egg lysozyme; MBP, myelin basic protein; MLN, mesenteric lymph node; NOD, nonobese diabetic; PLN, pancreatic lymph node; scTCR, single-chain TCR; sIA-Ig, soluble IA-Ig; SPR, surface plasmon resonance; TCR, T cell receptor; V, variable gene segment.

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تاریخ انتشار 2008